All eyes will be on left wrists players Novak Djokovic and Rafael Nadal in the season’s final Grand Slam US Open, kick-starting on Monday.
Defending champion Djokovic and fellow two-time winner Nadal come into this tournament with injury concerns.
World number one Djokovic, the 2011 and 2015 champion, admits he is “not 100%” after suffering a wrist injury on the eve of the Olympic Games.
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Nadal, meanwhile, is also battling the effects of a left wrist problem which forced a mid-tournament withdrawal from the French Open and sidelined him until the Olympics where he was a gold medal winner in the men’s doubles.
The injury concerns, combined with the absence for the first time since 1999 of 5-time winner Roger Federer, have put 2012 champion Andy Murray in the position of favorite.
Djokovic starts his bid for a third major of 2016, and 13th of his career, against Polish giant Jerzy Janowicz, who was a Wimbledon semi-finalist in 2013.
Nadal, the 2010 and 2013 champion in New York, tackles Denis Istomin of Uzbekistan.
Play on the cavernous Ashe stadium starts at 1500GMT.